Host: |
Rabbit |
Applications: |
ELISA/IHC/IP/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ITPR2 (100-150) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
FITC |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.66 µg/µl |
Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:100 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
Itpr2 |
Gene ID: |
81678 |
Uniprot ID: |
ITPR2_RAT |
Immunogen Region: |
100-150 |
Immunogen: |
Synthetic peptide taken within amino acid region 100-150 on rat Inosital 1, 4, 5-triphosphate receptor type 2 protein. |
Post Translational Modifications | Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release. |
Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA. |
Protein Name | Inositol 1 -4 -5-Trisphosphate Receptor Type 2Ip3 Receptor Isoform 2Ip3r 2Insp3r2Type 2 Inositol 1 -4 -5-Trisphosphate ReceptorType 2 Insp3 Receptor |
Database Links | Reactome: R-RNO-114508Reactome: -RNO-139853Reactome: -RNO-381676Reactome: -RNO-5578775Reactome: -RNO-983695 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 2 antibodyAnti-Ip3 Receptor Isoform 2 antibodyAnti-Ip3r 2 antibodyAnti-Insp3r2 antibodyAnti-Type 2 Inositol 1 -4 -5-Trisphosphate Receptor antibodyAnti-Type 2 Insp3 Receptor antibodyAnti-Itpr2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance