• Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from HT-29 cells, using IP3KC Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using InsP 3-kinase C Polyclonal Antibody diluted at 1：2000

Anti-ITPKC antibody (221-270 aa) (STJ93719)

SKU:
STJ93719

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Inositol-trisphosphate 3-kinase C (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITPKC
Gene ID: 80271
Uniprot ID: IP3KC_HUMAN
Immunogen Region: 221-270 aa
Specificity: InsP 3-kinase C Polyclonal Antibody detects endogenous levels of InsP 3-kinase C protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human IP3KC at the amino acid range 221-270
Function Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
Protein Name Inositol-Trisphosphate 3-Kinase C
Inositol 1 -4 -5-Trisphosphate 3-Kinase C
Ip3 3-Kinase C
Ip3k C
Insp 3-Kinase C
Database Links Reactome: R-HSA-1855204
Cellular Localisation Nucleus
Cytoplasm
Shuttles Actively Between Nucleus And Cytoplasm With Both Nuclear Import And Nuclear Export Activity
Alternative Antibody Names Anti-Inositol-Trisphosphate 3-Kinase C antibody
Anti-Inositol 1 -4 -5-Trisphosphate 3-Kinase C antibody
Anti-Ip3 3-Kinase C antibody
Anti-Ip3k C antibody
Anti-Insp 3-Kinase C antibody
Anti-ITPKC antibody
Anti-IP3KC antibody

Information sourced from Uniprot.org

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