| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Inositol-trisphosphate 3-kinase C (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITPKC |
| Gene ID: | 80271 |
| Uniprot ID: | IP3KC_HUMAN |
| Immunogen Region: | 221-270 aa |
| Specificity: | InsP 3-kinase C Polyclonal Antibody detects endogenous levels of InsP 3-kinase C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human IP3KC at the amino acid range 221-270 |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. |
| Protein Name | Inositol-Trisphosphate 3-Kinase C Inositol 1 -4 -5-Trisphosphate 3-Kinase C Ip3 3-Kinase C Ip3k C Insp 3-Kinase C |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | Nucleus Cytoplasm Shuttles Actively Between Nucleus And Cytoplasm With Both Nuclear Import And Nuclear Export Activity |
| Alternative Antibody Names | Anti-Inositol-Trisphosphate 3-Kinase C antibody Anti-Inositol 1 -4 -5-Trisphosphate 3-Kinase C antibody Anti-Ip3 3-Kinase C antibody Anti-Ip3k C antibody Anti-Insp 3-Kinase C antibody Anti-ITPKC antibody Anti-IP3KC antibody |
Information sourced from Uniprot.org