| Post Translational Modifications | N-glycosylated. |
| Function | Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind human glycans. Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption. |
| Protein Name | Intelectin-1Itln-1Endothelial Lectin Hl-1Galactofuranose-Binding LectinIntestinal Lactoferrin ReceptorOmentin |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecretedEnriched In Lipid Rafts |
| Alternative Antibody Names | Anti-Intelectin-1 antibodyAnti-Itln-1 antibodyAnti-Endothelial Lectin Hl-1 antibodyAnti-Galactofuranose-Binding Lectin antibodyAnti-Intestinal Lactoferrin Receptor antibodyAnti-Omentin antibodyAnti-ITLN1 antibodyAnti-INTL antibodyAnti-ITLN antibodyAnti-LFR antibodyAnti-UNQ640 antibodyAnti-PRO1270 antibody |
Information sourced from Uniprot.org
