| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-IRF6 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 58-60kDa band observed in Human Ovary and approx. 60kDa in Human Kidney lysates (calculated MW of 53.1kDa according to NP_006138.1).The observed molecular weight corresponds to d |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | IRF6 |
| Gene ID: | 3664 |
| Uniprot ID: | IRF6_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_006138.1 |
| Immunogen Sequence: | TPSMQLPPALPPQ |
| Post Translational Modifications | Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation. |
| Function | Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development. Plays a role in regulating mammary epithelial cell proliferation. May regulate WDR65 transcription. |
| Protein Name | Interferon Regulatory Factor 6Irf-6 |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-909733 |
| Cellular Localisation | NucleusCytoplasmTranslocates To Nucleus In Response To An Activating Signal |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 6 antibodyAnti-Irf-6 antibodyAnti-IRF6 antibody |
Information sourced from Uniprot.org