| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IRF2BP2 (475-545) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IRF2BP2 |
| Gene ID: |
359948 |
| Uniprot ID: |
I2BP2_HUMAN |
| Immunogen Region: |
475-545 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 475-545 of human IRF2BP2 (Q7Z5L9). |
| Immunogen Sequence: |
GGQGAGNTGGLEPVHPASLP DSSLATSAPLCCTLCHERLE DTHFVQCPSVPSHKFCFPCS RQSIKQQGASG |
| Post Translational Modifications | Phosphorylation at Ser-360 is required for nuclear targeting. |
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 2Irf-2-Binding Protein 2Irf-2bp2 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 2-Binding Protein 2 antibodyAnti-Irf-2-Binding Protein 2 antibodyAnti-Irf-2bp2 antibodyAnti-IRF2BP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
