Anti-IRF2BP2 antibody (475-545) (STJ119962)

Name: Anti-IRF2BP2 antibody (475-545) (STJ119962)
SKU: STJ119962
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119962

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Short Description	Rabbit polyclonal IRF2BP2 (475-545) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	IRF2BP2
Gene ID	359948
Uniprot ID	I2BP2_HUMAN
Immunogen Region	475-545
Immunogen Sequence	GGQGAGNTGGLEPVHPASLP DSSLATSAPLCCTLCHERLE DTHFVQCPSVPSHKFCFPCS RQSIKQQGASG
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 475-545 of human IRF2BP2 (Q7Z5L9).

Post Translational Modifications	Phosphorylation at Ser-360 is required for nuclear targeting.
Function	Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation.
Protein Name	Interferon Regulatory Factor 2-Binding Protein 2 Irf-2-Binding Protein 2 Irf-2bp2
Database Links
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Interferon Regulatory Factor 2-Binding Protein 2 antibody Anti-Irf-2-Binding Protein 2 antibody Anti-Irf-2bp2 antibody Anti-IRF2BP2 antibody

Information sourced from Uniprot.org