| Host: | Rabbit |
| Applications: | ICC/IHC-F/WB |
| Reactivity: | Cat/Human/Mouse/Other Mammals/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Internexin alpha for use in ICC, IHC-F and WB in Cat, Human, Mouse, Other Mammals and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | Mixed |
| Formulation: | Lyophilized with sodium azide. |
| Purification: | Whole serum |
| Dilution Range: | WB 1:10000-1:20000IHC 1:500-1:1000ICC 1:500-1:1000 |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for a higher stability. Avoid freeze-tha |
| Gene Symbol: | InaUniprot ID=AINX_RAT" |
| Specificity: | The specificity of this antibody has been confirmed by WB. This antibody is specific for the 64-66 kDa alpha-internexin protein. Molecular weight will depend on species. Hu, rat, Ms, Fel, and other mammals. |
| Immunogen: | Recombinant alpha-internexin expressed and purified from E. coli |
| Immunogen Sequence: | Rat |
| Tissue Specificity | Expressed in the dorsal root ganglion neurons (at protein level). |
| Post Translational Modifications | O-glycosylated. |
| Function | Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks. |
| Protein Name | Alpha-InternexinAlpha-Inx |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Alpha-Internexin antibodyAnti-Alpha-Inx antibodyAnti-Ina antibodyAnti-Inexa antibody |
Information sourced from Uniprot.org
