| Short Description : | Rabbit polyclonal INPP5J (60-360) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | INPP5J |
| Gene ID: | 27124 |
| Uniprot ID: | PI5PA_HUMAN |
| Immunogen Region: | 60-360 |
| Immunogen Sequence: | VTWNVGTAMPPDDVTSLLHL GGGDDSDGADMIAIGLQEVN SMLNKRLKDALFTDQWSELF MDALGPFNFVLVSSVRMQGV ILLLFAKYYHLPFLRDVQTD CTRTGLGGYWGNKGGVSVRL AAFGHMLCFLNCHLPAHMDK AEQRKDNFQTILSLQQFQGP GAQGILDHDLVFWFGDLNFR IESYDLHFVKFAIDSDQLHQ LWEKDQLNMAKNTWPILKGF QEGPLNFAPTFKFDVGTNK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1). |
| Function | Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles. |
| Protein Name | Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase AInositol Polyphosphate 5-Phosphatase JPhosphatidylinositol 1 -3 -4 -5-Tetrakisphosphate 5-PhosphatasePhosphatidylinositol 1 -4 -5-Trisphosphate 5-Phosphatase |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-1855183Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmPredominantly Localized To Membrane Ruffles |
| Alternative Antibody Names | Anti-Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase A antibodyAnti-Inositol Polyphosphate 5-Phosphatase J antibodyAnti-Phosphatidylinositol 1 -3 -4 -5-Tetrakisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol 1 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-INPP5J antibodyAnti-PIB5PA antibodyAnti-PIPP antibody |
Information sourced from Uniprot.org
