| Post Translational Modifications | Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference. |
| Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Protein Name | Inhibin Alpha Chain |
| Database Links | Reactome: R-HSA-1502540Reactome: R-HSA-201451Reactome: R-HSA-209822Reactome: R-HSA-9839406 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Inhibin Alpha Chain antibodyAnti-INHA antibody |
Information sourced from Uniprot.org
