Function | May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. |
Protein Name | Immunoglobulin-Like Domain-Containing Receptor 2Angulin-3 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionNucleus |
Alternative Antibody Names | Anti-Immunoglobulin-Like Domain-Containing Receptor 2 antibodyAnti-Angulin-3 antibodyAnti-ILDR2 antibodyAnti-C1orf32 antibody |
Information sourced from Uniprot.org