| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/FC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200FC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL2RA |
| Gene ID: | 3559 |
| Uniprot ID: | IL2RA_HUMAN |
| Immunogen Region: | 153-167 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 101-200 of human CD25 (NP_000408.1). |
| Immunogen Sequence: | QKERKTTEMQSPMQPVDQAS LPGHCREPPPWENEATERIY HFVVGQMVYYQCVQGYRALH RGPAESVCKMTHGKTRWTQP QLICTGEMETSQFPGEEKPQ ASPEGRPESETSCLVTTTDF QIQTEMAATMETSIFTTEYQ VAVAGCVFLLISVLLLSGLT WQRRQRKSRRTI |
| Function | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. |
| Protein Name | Interleukin-2 Receptor Subunit AlphaIl-2 Receptor Subunit AlphaIl-2-RaIl-2r Subunit AlphaIl2-RaTac AntigenP55Cd Antigen Cd25 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8877330Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Alpha antibodyAnti-Il-2 Receptor Subunit Alpha antibodyAnti-Il-2-Ra antibodyAnti-Il-2r Subunit Alpha antibodyAnti-Il2-Ra antibodyAnti-Tac Antigen antibodyAnti-P55 antibodyAnti-Cd Antigen Cd25 antibodyAnti-IL2RA antibody |
Information sourced from Uniprot.org