Anti-IL27RA antibody (STJ192032)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-27 receptor subunit alpha for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL27RA |
| Gene ID | 9466 |
| Uniprot ID | I27RA_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | I27RA Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. |
| Protein Name | Interleukin-27 Receptor Subunit AlphaIl-27 Receptor Subunit AlphaIl-27r Subunit AlphaIl-27r-AlphaIl-27raCytokine Receptor Wsx-1Cytokine Receptor-Like 1Type I T-Cell Cytokine ReceptorTccrZcytor1 |
| Database Links | Reactome: R-HSA-8984722Reactome: R-HSA-9020956 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-27 Receptor Subunit Alpha antibodyAnti-Il-27 Receptor Subunit Alpha antibodyAnti-Il-27r Subunit Alpha antibodyAnti-Il-27r-Alpha antibodyAnti-Il-27ra antibodyAnti-Cytokine Receptor Wsx-1 antibodyAnti-Cytokine Receptor-Like 1 antibodyAnti-Type I T-Cell Cytokine Receptor antibodyAnti-Tccr antibodyAnti-Zcytor1 antibodyAnti-IL27RA antibodyAnti-CRL1 antibodyAnti-TCCR antibodyAnti-WSX1 antibodyAnti-UNQ296 antibodyAnti-PRO336 antibody |
Information sourced from Uniprot.org