Function | May play a role in local mechanisms of mucosal immunity and seems to have a pro-inflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. |
Protein Name | Interleukin-26Il-26Protein Ak155 |
Database Links | Reactome: R-HSA-8854691 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Interleukin-26 antibodyAnti-Il-26 antibodyAnti-Protein Ak155 antibodyAnti-IL26 antibodyAnti-AK155 antibody |
Information sourced from Uniprot.org