Anti-IL21 antibody [SAA0390] {PE} (STJA0031607)

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STJA0031607-100
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Short Description :Mouse monoclonal Interleukin-21 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0390
Isotype:IgG1k
Conjugation:PE
Concentration:0.5 mg/mL
Purification:Purified
Formulation:PBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage Instruction:Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol:IL21
Gene ID:59067
Uniprot ID:IL21_HUMAN
Function Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Protein Name Interleukin-21
Il-21
Za11
Database Links Reactome: R-HSA-9020958
Cellular Localisation Secreted
Alternative Antibody Names Anti-Interleukin-21 antibody
Anti-Il-21 antibody
Anti-Za11 antibody
Anti-IL21 antibody

Information sourced from Uniprot.org

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