Anti-IL18R1 antibody (231-280 aa) (STJ96837)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL18R1 at the amino acid range 231-280
General Information
| Short Description | Rabbit polyclonal anti-Interleukin-18 receptor 1 (231-280 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL18R1 |
| Gene ID | 8809 |
| Uniprot ID | IL18R_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IL18R1 at the amino acid range 231-280 |
| Immunogen Region | 231-280 aa |
| Specificity | IL-18R Polyclonal Antibody detects endogenous levels of IL-18R protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex. |
| Function | Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3. |
| Protein Name | Interleukin-18 Receptor 1Il-18r-1Il-18r1Cd218 Antigen-Like Family Member ACdw218aIl1 Receptor-Related ProteinIl-1rrpIl1r-RpInterleukin-18 Receptor AlphaIl-18r-AlphaIl-18ralphaCd Antigen Cd218a |
| Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-18 Receptor 1 antibodyAnti-Il-18r-1 antibodyAnti-Il-18r1 antibodyAnti-Cd218 Antigen-Like Family Member A antibodyAnti-Cdw218a antibodyAnti-Il1 Receptor-Related Protein antibodyAnti-Il-1rrp antibodyAnti-Il1r-Rp antibodyAnti-Interleukin-18 Receptor Alpha antibodyAnti-Il-18r-Alpha antibodyAnti-Il-18ralpha antibodyAnti-Cd Antigen Cd218a antibodyAnti-IL18R1 antibodyAnti-IL1RRP antibody |
Information sourced from Uniprot.org