Anti-IL18R1 antibody (231-280 aa) (STJ96837)

SKU:
STJ96837
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Interleukin-18 receptor 1 (231-280 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
ELISA 1:20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:IL18R1
Gene ID:8809
Uniprot ID:IL18R_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human IL18R1 at the amino acid range 231-280
Immunogen Region:231-280 aa
Specificity:IL-18R Polyclonal Antibody detects endogenous levels of IL-18R protein.
Post Translational Modifications N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex.
Function Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.
Protein Name Interleukin-18 Receptor 1
Il-18r-1
Il-18r1
Cd218 Antigen-Like Family Member A
Cdw218a
Il1 Receptor-Related Protein
Il-1rrp
Il1r-Rp
Interleukin-18 Receptor Alpha
Il-18r-Alpha
Il-18ralpha
Cd Antigen Cd218a
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-18 Receptor 1 antibody
Anti-Il-18r-1 antibody
Anti-Il-18r1 antibody
Anti-Cd218 Antigen-Like Family Member A antibody
Anti-Cdw218a antibody
Anti-Il1 Receptor-Related Protein antibody
Anti-Il-1rrp antibody
Anti-Il1r-Rp antibody
Anti-Interleukin-18 Receptor Alpha antibody
Anti-Il-18r-Alpha antibody
Anti-Il-18ralpha antibody
Anti-Cd Antigen Cd218a antibody
Anti-IL18R1 antibody
Anti-IL1RRP antibody

Information sourced from Uniprot.org