Host: |
Mouse |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Interleukin-18-binding protein is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
5C7-D2-G4-B6 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2b |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:400 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
IL18BP |
Gene ID: |
10068 |
Uniprot ID: |
I18BP_HUMAN |
Specificity: |
This antibody detects endogenous levels of IL18 binding protein and does not cross-react with related proteins. |
Immunogen: |
Purified recombinant human IL18 binding protein protein fragments expressed in E.coli. |
Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4. |
Function | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. |
Protein Name | Interleukin-18-Binding ProteinIl-18bpTadekinig-Alfa |
Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Interleukin-18-Binding Protein antibodyAnti-Il-18bp antibodyAnti-Tadekinig-Alfa antibodyAnti-IL18BP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance