Function | Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. |
Protein Name | Interleukin-17 Receptor EIl-17 Receptor EIl-17re |
Database Links | Reactome: R-HSA-448424 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: CytoplasmIsoform 3: SecretedIsoform 4: CytoplasmIsoform 5: Secreted |
Alternative Antibody Names | Anti-Interleukin-17 Receptor E antibodyAnti-Il-17 Receptor E antibodyAnti-Il-17re antibodyAnti-IL17RE antibodyAnti-UNQ3056 antibodyAnti-PRO9877 antibody |
Information sourced from Uniprot.org