• Western blot analysis of various lysates using IL17RE Rabbit polyclonal antibody (STJ116527) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-IL17RE antibody (24-260) (STJ116527)

SKU:
STJ116527

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IL17RE (24-260) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL17RE
Gene ID: 132014
Uniprot ID: I17RE_HUMAN
Immunogen Region: 24-260
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_705613.1).
Immunogen Sequence: AGIGFRHLPHWNTRCPLASH TDDSFTGSSAYIPCRTWWAL FSTKPWCVRVWHCSRCLCQH LLSGGSGLQRGLFHLLVQKS KKSSTFKFYRRHKMPAPAQR KLLPRRHLSEKSHHISIPSP DISHKGLRSKRTQPSDPETW ESLPRLDSQRHGGPEFSFDL LPEARAIRVTISSGPEVSVR LCHQWALECEELSSPYDVQK IVSGGHTVELPYEFLLPCLC IEASYLQEDTVRRKKCP
Tissue Specificity Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
Function Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
Protein Name Interleukin-17 Receptor E
Il-17 Receptor E
Il-17re
Database Links Reactome: R-HSA-448424
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cytoplasm
Isoform 3: Secreted
Isoform 4: Cytoplasm
Isoform 5: Secreted
Alternative Antibody Names Anti-Interleukin-17 Receptor E antibody
Anti-Il-17 Receptor E antibody
Anti-Il-17re antibody
Anti-IL17RE antibody
Anti-UNQ3056 antibody
Anti-PRO9877 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance