| Short Description : | Rabbit polyclonal IL17RB (18-292) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL17RB |
| Gene ID: | 55540 |
| Uniprot ID: | I17RB_HUMAN |
| Immunogen Region: | 18-292 |
| Immunogen Sequence: | REPTVQCGSETGPSPEWMLQ HDLIPGDLRDLRVEPVTTSV ATGDYSILMNVSWVLRADAS IRLLKATKICVTGKSNFQSY SCVRCNYTEAFQTQTRPSGG KWTFSYIGFPVELNTVYFIG AHNIPNANMNEDGPSMSVNF TSPGCLDHIMKYKKKCVKAG SLWDPNITACKKNEETVEVN FTTTPLGNRYMALIQHSTII GFSQVFEPHQKKQTRASVVI PVTGDSEGATVQLTPYFPT |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2). |
| Tissue Specificity | Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine.not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. |
| Function | Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. |
| Protein Name | Interleukin-17 Receptor BIl-17 Receptor BIl-17rbCytokine Receptor-Like 4Il-17 Receptor Homolog 1Il-17rh1Il17rh1Interleukin-17b ReceptorIl-17b Receptor |
| Database Links | Reactome: R-HSA-448424 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Interleukin-17 Receptor B antibodyAnti-Il-17 Receptor B antibodyAnti-Il-17rb antibodyAnti-Cytokine Receptor-Like 4 antibodyAnti-Il-17 Receptor Homolog 1 antibodyAnti-Il-17rh1 antibodyAnti-Il17rh1 antibodyAnti-Interleukin-17b Receptor antibodyAnti-Il-17b Receptor antibodyAnti-IL17RB antibodyAnti-CRL4 antibodyAnti-EVI27 antibodyAnti-IL17BR antibodyAnti-UNQ2501 antibodyAnti-PRO19612 antibody |
Information sourced from Uniprot.org
![Anti-IL17RB nanobody [SAA1267] (STJN000305)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/200918/413100/STJN000305-SDS-PAGE-1__99565.1749232601.jpg?c=1 "Anti-IL17RB nanobody [SAA1267] (STJN000305)")
