Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | IL17RB |
Gene ID: | 55540 |
Uniprot ID: | I17RB_HUMAN |
Immunogen Region: | 18-292 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2). |
Immunogen Sequence: | REPTVQCGSETGPSPEWMLQ HDLIPGDLRDLRVEPVTTSV ATGDYSILMNVSWVLRADAS IRLLKATKICVTGKSNFQSY SCVRCNYTEAFQTQTRPSGG KWTFSYIGFPVELNTVYFIG AHNIPNANMNEDGPSMSVNF TSPGCLDHIMKYKKKCVKAG SLWDPNITACKKNEETVEVN FTTTPLGNRYMALIQHSTII GFSQVFEPHQKKQTRASVVI PVTGDSEGATVQLTPYFPT |
Tissue Specificity | Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine.not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. |
Function | Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. |
Protein Name | Interleukin-17 Receptor BIl-17 Receptor BIl-17rbCytokine Receptor-Like 4Il-17 Receptor Homolog 1Il-17rh1Il17rh1Interleukin-17b ReceptorIl-17b Receptor |
Database Links | Reactome: R-HSA-448424 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Antibody Names | Anti-Interleukin-17 Receptor B antibodyAnti-Il-17 Receptor B antibodyAnti-Il-17rb antibodyAnti-Cytokine Receptor-Like 4 antibodyAnti-Il-17 Receptor Homolog 1 antibodyAnti-Il-17rh1 antibodyAnti-Il17rh1 antibodyAnti-Interleukin-17b Receptor antibodyAnti-Il-17b Receptor antibodyAnti-IL17RB antibodyAnti-CRL4 antibodyAnti-EVI27 antibodyAnti-IL17BR antibodyAnti-UNQ2501 antibodyAnti-PRO19612 antibody |
Information sourced from Uniprot.org