| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Interleukin-13 receptor subunit alpha-2 (241-290 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL13RA2 |
| Gene ID: | 3598 |
| Uniprot ID: | I13R2_HUMAN |
| Immunogen Region: | 241-290 aa |
| Specificity: | IL-13R Alpha 2 Polyclonal Antibody detects endogenous levels of IL-13R Alpha 2 protein. |
| Immunogen: | Synthesized peptide derived from Interleukin-13 receptor subunit alpha-2 at the amino acid range 241-290 |
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-2Il-13 Receptor Subunit Alpha-2Il-13r Subunit Alpha-2Il-13r-Alpha-2Il-13ra2Interleukin-13-Binding ProteinCd Antigen Cd213a2 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13 Receptor Subunit Alpha-2 antibodyAnti-Il-13r Subunit Alpha-2 antibodyAnti-Il-13r-Alpha-2 antibodyAnti-Il-13ra2 antibodyAnti-Interleukin-13-Binding Protein antibodyAnti-Cd Antigen Cd213a2 antibodyAnti-IL13RA2 antibodyAnti-IL13R antibody |
Information sourced from Uniprot.org