Anti-IL-5 Receptor alpha antibody [R55-3N-3] (STJA0035618)

SKU:
STJA0035618
€166.88 - €351.88
Processing The item has been added

Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-IL-5 Receptor alpha for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R55-3N-3
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: IL5RA
Gene ID: 3568
Uniprot ID: IL5RA_HUMAN
Immunogen: A synthesized peptide derived from human CD125
Tissue Specificity Expressed on eosinophils and basophils.
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Interleukin-5 Receptor Subunit Alpha
Il-5 Receptor Subunit Alpha
Il-5r Subunit Alpha
Il-5r-Alpha
Il-5ra
Cdw125
Cd Antigen Cd125
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-5 Receptor Subunit Alpha antibody
Anti-Il-5 Receptor Subunit Alpha antibody
Anti-Il-5r Subunit Alpha antibody
Anti-Il-5r-Alpha antibody
Anti-Il-5ra antibody
Anti-Cdw125 antibody
Anti-Cd Antigen Cd125 antibody
Anti-IL5RA antibody
Anti-IL5R antibody

Information sourced from Uniprot.org