Tissue Specificity | Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. |
Post Translational Modifications | N-glycosylated. Isoform 4 is glycosylated at Asn-154. |
Function | Target of p53/TP53 with pro-apoptotic function. |
Protein Name | Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting ProteinI Kappa-B Kinase-Interacting ProteinIkbkb-Interacting ProteinIkk-Interacting Protein |
Database Links | Reactome: R-HSA-9758274 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIsoform 4 Deletion Of The HydrophobicOr Transmembrane Region Between Aa 45-63 Results In Uniform Distribution Throughout The CellSuggesting That This Region Is Responsible For Endoplasmic Reticulum Localization |
Alternative Antibody Names | Anti-Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein antibodyAnti-I Kappa-B Kinase-Interacting Protein antibodyAnti-Ikbkb-Interacting Protein antibodyAnti-Ikk-Interacting Protein antibodyAnti-IKBIP antibodyAnti-IKIP antibody |
Information sourced from Uniprot.org