Anti-IKB epsilon antibody [R05-1B2] (STJA0035235)

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STJA0035235
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-IKB epsilon for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R05-1B2
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: NFKBIE
Gene ID: 4794
Uniprot ID: IKBE_HUMAN
Immunogen: A synthetic peptide of human IKB epsilon
Tissue Specificity Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages.
Post Translational Modifications Serine phosphorylated.followed by proteasome-dependent degradation.
Function Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity. Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes. Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development.
Protein Name Nf-Kappa-B Inhibitor Epsilon
Nf-Kappa-Bie
I-Kappa-B-Epsilon
Ikb-E
Ikb-Epsilon
Ikappabepsilon
Database Links Reactome: R-HSA-1169091
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Nf-Kappa-B Inhibitor Epsilon antibody
Anti-Nf-Kappa-Bie antibody
Anti-I-Kappa-B-Epsilon antibody
Anti-Ikb-E antibody
Anti-Ikb-Epsilon antibody
Anti-Ikappabepsilon antibody
Anti-NFKBIE antibody
Anti-IKBE antibody

Information sourced from Uniprot.org

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