| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-IGFBP7 (145-159) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 30kDa band observed in Mouse Kidney lysates (calculated MW of 29.1kDa according to Human NP_001544.1 and to Mouse NP_032074.3). Recommended concentration: 1-3µg/ml. Primary incub |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | IGFBP7 |
| Gene ID: | 3490 |
| Uniprot ID: | IBP7_HUMAN |
| Immunogen Region: | 145-159 |
| Accession Number: | NP_001544.1 |
| Immunogen Sequence: | EKAITQVSKGTCEQG |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin-Like Growth Factor-Binding Protein 7 antibodyAnti-Ibp-7 antibodyAnti-Igf-Binding Protein 7 antibodyAnti-Igfbp-7 antibodyAnti-Igfbp-Rp1 antibodyAnti-Mac25 Protein antibodyAnti-Pgi2-Stimulating Factor antibodyAnti-Prostacyclin-Stimulating Factor antibodyAnti-Tumor-Derived Adhesion Factor antibodyAnti-Taf antibodyAnti-IGFBP7 antibodyAnti-MAC25 antibodyAnti-PSF antibody |
Information sourced from Uniprot.org