| Function | Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells. |
| Protein Name | Intraflagellar Transport Protein 140 HomologWd And Tetratricopeptide Repeats Protein 2 |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCell ProjectionCilium |
| Alternative Antibody Names | Anti-Intraflagellar Transport Protein 140 Homolog antibodyAnti-Wd And Tetratricopeptide Repeats Protein 2 antibodyAnti-IFT140 antibodyAnti-KIAA0590 antibodyAnti-WDTC2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and HNRNPR knockout (KO) 293T cells, using [KO Validated] HNRNPR Rabbit polyclonal antibody (STJ11100875) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89809/358275/STJ11100875_1__14714.1713122621.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and HNRNPR knockout (KO) 293T cells, using [KO Validated] HNRNPR Rabbit polyclonal antibody (STJ11100875) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
