Anti-IFT140 antibody (550-800 aa) (STJ11106532)

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STJ11106532
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: IFT140
Gene ID: 9742
Uniprot ID: IF140_HUMAN
Immunogen Region: 550-800 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human IFT140 (NP_055529.2).
Immunogen Sequence: RREAKAHCSCRSLAELVPGV GGIASLRCSSSGSTISILPS KADNSPDSKICFYDVEMDTV TVFDFKTGQIDRRETLSFNE QETNKSHLFVDEGLKNYVPV NHFWDQSEPRLFVCEAVQET PRSQPQSANGQPQDGRAGPA ADVLILSFFISEEHGFLLHE SFPRPATSHSLLGMEVPYYY FTRKPEEADREDEVEPGCHH IPQMVSRRPLRDFVGLEDCD KATRDAMLHFSFFVTIGDM
Function Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells.
Protein Name Intraflagellar Transport Protein 140 Homolog
Wd And Tetratricopeptide Repeats Protein 2
Database Links Reactome: R-HSA-5610787
Reactome: R-HSA-5620924
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Basal Body
Microtubule Organizing Center
Centrosome
Cell Projection
Cilium
Alternative Antibody Names Anti-Intraflagellar Transport Protein 140 Homolog antibody
Anti-Wd And Tetratricopeptide Repeats Protein 2 antibody
Anti-IFT140 antibody
Anti-KIAA0590 antibody
Anti-WDTC2 antibody

Information sourced from Uniprot.org

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