| Short Description : | Rabbit polyclonal ID4 (1-100) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ID4 |
| Gene ID: | 3400 |
| Uniprot ID: | ID4_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MKAVSPVRPSGRKAPSGCGG GELALRCLAEHGHSLGGSAA AAAAAAAARCKAAEAAADEP ALCLQCDMNDCYSRLRRLVP TIPPNKKVSKVEILQHVIDY |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ID4 (NP_001537.1). |
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. |
| Protein Name | Dna-Binding Protein Inhibitor Id-4Class B Basic Helix-Loop-Helix Protein 27Bhlhb27Inhibitor Of Dna Binding 4Inhibitor Of Differentiation 4 |
| Database Links | Reactome: R-HSA-9031628Reactome: R-HSA-9830364 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna-Binding Protein Inhibitor Id-4 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 27 antibodyAnti-Bhlhb27 antibodyAnti-Inhibitor Of Dna Binding 4 antibodyAnti-Inhibitor Of Differentiation 4 antibodyAnti-ID4 antibodyAnti-BHLHB27 antibody |
Information sourced from Uniprot.org
