Anti-ID1 antibody [R01-2A4] (STJA0035771)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Id1
General Information
| Short Description | Rabbit monoclonal anti-ID1 for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-2A4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ID1 |
| Gene ID | 3397 |
| Uniprot ID | ID1_HUMAN |
| Immunogen | A synthesized peptide derived from human Id1 |
Additional Info
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. |
| Protein Name | Dna-Binding Protein Inhibitor Id-1Class B Basic Helix-Loop-Helix Protein 24Bhlhb24Inhibitor Of Dna Binding 1Inhibitor Of Differentiation 1 |
| Database Links | Reactome: R-HSA-2559585Reactome: R-HSA-9031628Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dna-Binding Protein Inhibitor Id-1 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 24 antibodyAnti-Bhlhb24 antibodyAnti-Inhibitor Of Dna Binding 1 antibodyAnti-Inhibitor Of Differentiation 1 antibodyAnti-ID1 antibodyAnti-BHLHB24 antibodyAnti-ID antibody |
Information sourced from Uniprot.org