• Immunofluorescence analysis of A549 cells, using CD50/ICAM-3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from NIH/3T3 cells, treated with TNF-a 20ng/ml 5', using CD50/ICAM-3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of NIH-3T3 cells using CD50 Polyclonal Antibody

Anti-ICAM3 antibody (484-533 aa) (STJ92132)

SKU:
STJ92132

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Intercellular adhesion molecule 3 (484-533 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ICAM3
Gene ID: 3385
Uniprot ID: ICAM3_HUMAN
Immunogen Region: 484-533 aa
Specificity: CD50 Polyclonal Antibody detects endogenous levels of CD50 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CD50/ICAM-3 at the amino acid range 484-533
Post Translational Modifications Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name Intercellular Adhesion Molecule 3
Icam-3
Cdw50
Icam-R
Cd Antigen Cd50
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 3 antibody
Anti-Icam-3 antibody
Anti-Cdw50 antibody
Anti-Icam-R antibody
Anti-Cd Antigen Cd50 antibody
Anti-ICAM3 antibody

Information sourced from Uniprot.org

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