• Western blot analysis of U-937, using ICAM3 antibody (STJ24116) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-ICAM3 antibody (270-490) (STJ24116)

SKU:
STJ24116

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ICAM3 (270-490) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ICAM3
Gene ID: 3385
Uniprot ID: ICAM3_HUMAN
Immunogen Region: 270-490
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-490 of human ICAM3 (NP_002153.2).
Immunogen Sequence: HGDTLTATATATARADQEGA REIVCNVTLGGERREARENL TVFSFLGPIVNLSEPTAHEG STVTVSCMAGARVQVTLDGV PAAAPGQPAQLQLNATESDD GRSFFCSATLEVDGEFLHRN SSVQLRVLYGPKIDRATCPQ HLKWKDKTRHVLQCQARGNP YPELRCLKEGSSREVPVGIP FFVNVTHNGTYQCQASSSRG KYTLVVVMDIEAGSSHFVPV F
Tissue Specificity Leukocytes.
Post Translational Modifications Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name Intercellular Adhesion Molecule 3
Icam-3
Cdw50
Icam-R
Cd Antigen Cd50
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 3 antibody
Anti-Icam-3 antibody
Anti-Cdw50 antibody
Anti-Icam-R antibody
Anti-Cd Antigen Cd50 antibody
Anti-ICAM3 antibody

Information sourced from Uniprot.org

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