| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ICAM2 |
| Gene ID: | 3384 |
| Uniprot ID: | ICAM2_HUMAN |
| Immunogen Region: | 25-223 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2). |
| Immunogen Sequence: | KVFEVHVRPKKLAVEPKGSL EVNCSTTCNQPEVGGLETSL DKILLDEQAQWKHYLVSNIS HDTVLQCHFTCSGKQESMNS NVSVYQPPRQVILTLQPTLV AVGKSFTIECRVPTVEPLDS LTLFLFRGNETLHYETFGKA APAPQEATATFNSTADREDG HRNFSCLAVLDLMSRGGNIF HKHSAPKMLEIYEPVSDSQ |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
| Protein Name | Intercellular Adhesion Molecule 2Icam-2Cd Antigen Cd102 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083Reactome: R-HSA-5621575 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Cd Antigen Cd102 antibodyAnti-ICAM2 antibody |
Information sourced from Uniprot.org