Anti-ICAM-1/CD54 antibody [SRM14759] (STJ11109489)

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STJ11109489
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Host: Rabbit
Applications: WB/IF-P/IHC-P/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14759
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:6000-1:36000
IF-P, 1:200-1:800
IHC-P, 1:1000-1:4000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Icam1
Gene ID: 15894
Uniprot ID: ICAM1_MOUSE
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.
Post Translational Modifications Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Mala-2
Myd10
Cd Antigen Cd54
Database Links Reactome: R-MMU-198933
Reactome: -MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Mala-2 antibody
Anti-Myd10 antibody
Anti-Cd Antigen Cd54 antibody
Anti-Icam1 antibody
Anti-Icam-1 antibody

Information sourced from Uniprot.org

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