| Host: | Rabbit |
| Applications: | WB/IHC-P/FC/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM13497 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB, 1:5000-1:20000IHC-P, 1:200-1:800FC, 1:500-1:1000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Icam1 |
| Gene ID: | 25464 |
| Uniprot ID: | ICAM1_RAT |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence: | Rat |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
| Protein Name | Intercellular Adhesion Molecule 1Icam-1Cd Antigen Cd54 |
| Database Links | Reactome: R-RNO-198933Reactome: -RNO-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 1 antibodyAnti-Icam-1 antibodyAnti-Cd Antigen Cd54 antibodyAnti-Icam1 antibodyAnti-Icam-1 antibody |
Information sourced from Uniprot.org