| Host: | Rabbit |
| Applications: | IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 7 (391-440 aa) is suitable for use in Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HTR7 |
| Gene ID: | 3363 |
| Uniprot ID: | 5HT7R_HUMAN |
| Immunogen Region: | 391-440 aa |
| Specificity: | SR-7 Polyclonal Antibody detects endogenous levels of SR-7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human HTR7 at the amino acid range 391-440 |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 75-Ht-75-Ht75-Ht-XSerotonin Receptor 7 |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418555Reactome: R-HSA-9706019 P34969-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 7 antibodyAnti-5-Ht-7 antibodyAnti-5-Ht7 antibodyAnti-5-Ht-X antibodyAnti-Serotonin Receptor 7 antibodyAnti-HTR7 antibody |
Information sourced from Uniprot.org
