Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 1D (120-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HTR1D |
Gene ID: |
3352 |
Uniprot ID: |
5HT1D_HUMAN |
Immunogen Region: |
120-200 aa |
Specificity: |
SR-1D Polyclonal Antibody detects endogenous levels of SR-1D protein. |
Immunogen: |
Synthesized peptide derived from SR-1D at the amino acid range 120-200 |
Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. |
Protein Name | 5-Hydroxytryptamine Receptor 1d5-Ht-1d5-Ht1dSerotonin 1d Alpha Receptor5-Ht-1d-AlphaSerotonin Receptor 1d |
Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 1d antibodyAnti-5-Ht-1d antibodyAnti-5-Ht1d antibodyAnti-Serotonin 1d Alpha Receptor antibodyAnti-5-Ht-1d-Alpha antibodyAnti-Serotonin Receptor 1d antibodyAnti-HTR1D antibodyAnti-HTR1DA antibodyAnti-HTRL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance