| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Oxidoreductase HTATIP2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HTATIP2 |
| Gene ID: | 10553 |
| Uniprot ID: | HTAI2_HUMAN |
| Specificity: | This antibody detects endogenous levels of TIP30 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human TIP30 |
| Function | Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. |
| Protein Name | Oxidoreductase Htatip230 Kda Hiv-1 Tat-Interacting ProteinHiv-1 Tat-Interactive Protein 2 |
| Cellular Localisation | CytoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Oxidoreductase Htatip2 antibodyAnti-30 Kda Hiv-1 Tat-Interacting Protein antibodyAnti-Hiv-1 Tat-Interactive Protein 2 antibodyAnti-HTATIP2 antibodyAnti-CC3 antibodyAnti-TIP30 antibody |
Information sourced from Uniprot.org