• Western blot analysis of lysates from HeLa cells, using HSP105 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HeLa cells, using HSP105 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using HSP105 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using HSP105 Polyclonal Antibody

Anti-HSPH1 antibody (791-840 aa) (STJ93614)

SKU:
STJ93614

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Heat shock protein 105 kDa (791-840 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSPH1
Gene ID: 10808
Uniprot ID: HS105_HUMAN
Immunogen Region: 791-840 aa
Specificity: HSP105 Polyclonal Antibody detects endogenous levels of HSP105 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HSP105 at the amino acid range 791-840
Post Translational Modifications Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Function Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Protein Name Heat Shock Protein 105 Kda
Antigen Ny-Co-25
Heat Shock 110 Kda Protein
Database Links Reactome: R-HSA-3000484
Reactome: R-HSA-3371453
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Heat Shock Protein 105 Kda antibody
Anti-Antigen Ny-Co-25 antibody
Anti-Heat Shock 110 Kda Protein antibody
Anti-HSPH1 antibody
Anti-HSP105 antibody
Anti-HSP110 antibody
Anti-KIAA0201 antibody

Information sourced from Uniprot.org

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