Anti-HspB8 antibody [R05-1J2] (STJA0036192)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human HSPB8/HSP22
General Information
| Short Description | Rabbit monoclonal anti-HspB8 for use in WB, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-1J2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HSPB8 |
| Gene ID | 26353 |
| Uniprot ID | HSPB8_HUMAN |
| Immunogen | A synthesized peptide derived from human HSPB8/HSP22 |
Additional Info
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart. |
| Function | Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8Hspb8Alpha-Crystallin C ChainE2-Induced Gene 1 ProteinHeat Shock Protein Family B Member 8Protein Kinase H11Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | CytoplasmNucleusTranslocates To Nuclear Foci During Heat Shock |
| Alternative Antibody Names | Anti-Heat Shock Protein Beta-8 antibodyAnti-Hspb8 antibodyAnti-Alpha-Crystallin C Chain antibodyAnti-E2-Induced Gene 1 Protein antibodyAnti-Heat Shock Protein Family B Member 8 antibodyAnti-Protein Kinase H11 antibodyAnti-Small Stress Protein-Like Protein Hsp22 antibodyAnti-HSPB8 antibodyAnti-CRYAC antibodyAnti-E2IG1 antibodyAnti-HSP22 antibodyAnti-PP1629 antibody |
Information sourced from Uniprot.org