Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Grp75 (580-679) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S6MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HSPA9 |
Gene ID: |
3313 |
Uniprot ID: |
GRP75_HUMAN |
Immunogen Region: |
580-679 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 580-679 of human Grp75/MOT/HSPA9 (P38646). |
Immunogen Sequence: |
EAVNMAEGIIHDTETKMEEF KDQLPADECNKLKEEISKMR ELLARKDSETGENIRQAASS LQQASLKLFEMAYKKMASER EGSGSSGTGEQKEDQKEEKQ |
Function | Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. |
Protein Name | Stress-70 Protein - Mitochondrial75 Kda Glucose-Regulated ProteinGrp-75Heat Shock 70 Kda Protein 9MortalinMotPeptide-Binding Protein 74Pbp74 |
Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-3371453Reactome: R-HSA-8949613Reactome: R-HSA-8950505 |
Cellular Localisation | MitochondrionNucleusNucleolus |
Alternative Antibody Names | Anti-Stress-70 Protein - Mitochondrial antibodyAnti-75 Kda Glucose-Regulated Protein antibodyAnti-Grp-75 antibodyAnti-Heat Shock 70 Kda Protein 9 antibodyAnti-Mortalin antibodyAnti-Mot antibodyAnti-Peptide-Binding Protein 74 antibodyAnti-Pbp74 antibodyAnti-HSPA9 antibodyAnti-GRP75 antibodyAnti-HSPA9B antibodyAnti-mt-HSP70 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance