| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HSD17B7 |
| Gene ID: |
51478 |
| Uniprot ID: |
DHB7_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HSD17B7 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human HSD17B7 |
| Post Translational Modifications | Phosphorylated. |
| Function | Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis. Catalyzes the NADP(H)-dependent reduction of estrogens and androgens and regulates the biological potency of these steroids. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Converts dihydrotestosterone (DHT) to its inactive form 5a-androstane-3b,17b-diol. Converts moderately progesterone to 3beta-hydroxypregn-4-ene-20-one, leading to its inactivation. Additionally, participates in the post-squalene cholesterol biosynthesis, as a 3-ketosteroid reductase. Isoform 3: Does not have enzymatic activities toward E1 and DHT. |
| Protein Name | 3-Keto-Steroid Reductase/17-Beta-Hydroxysteroid Dehydrogenase 717-Beta-Hydroxysteroid Dehydrogenase 717-Beta-Hsd 73-Keto-Steroid ReductaseDihydrotestosterone OxidoreductaseEstradiol 17-Beta-Dehydrogenase 7Short Chain Dehydrogenase/Reductase Family 37c Member 1 |
| Database Links | Reactome: R-HSA-191273 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-3-Keto-Steroid Reductase/17-Beta-Hydroxysteroid Dehydrogenase 7 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase 7 antibodyAnti-17-Beta-Hsd 7 antibodyAnti-3-Keto-Steroid Reductase antibodyAnti-Dihydrotestosterone Oxidoreductase antibodyAnti-Estradiol 17-Beta-Dehydrogenase 7 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 37c Member 1 antibodyAnti-HSD17B7 antibodyAnti-17HSD7 antibodyAnti-SDR37C1 antibodyAnti-UNQ2563 antibodyAnti-PRO6243 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
