• Immunofluorescence analysis of paraffin-embedded Human liver using HSD17B13 Rabbit polyclonal antibody (STJ11105579) at a dilution of 1:200 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of Hep G2 cells using HSD17B13 Rabbit polyclonal antibody (STJ11105579) at a dilution of 1:200 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of lysates from Rat pancreas using HSD17B13 Rabbit polyclonal antibody (STJ11105579) at 1:2000 dilution. Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection:ECL Basic Kit. Exposuretime:20s.

Anti-HSD17B13 antibody (34-300) (STJ11105579)

SKU:
STJ11105579

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-17-Beta-Hydroxysteroid Dehydrogenase 13 (34-300) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
IF/ICC 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSD17B13
Gene ID: 345275
Uniprot ID: DHB13_HUMAN
Immunogen Region: 34-300
Immunogen: Recombinant Protein corresponding to a sequence within amino acids 34-300 of human HSD17B13 (NP_835236.2).
Immunogen Sequence: VAGEIVLITGAGHGIGRQTT YEFAKRQSILVLWDINKRGV EETAAECRKLGVTAHAYVVD CSNREEIYRSLNQVKKEVGD VTIVVNNAGTVYPADLLSTK DEEITKTFEVNILGHFWITK ALLPSMMERNHGHIVTVASV CGHEGIPYLIPYCSSKFAAV GFHRGLTSELQALGKTGIKT SCLCPVFVNTGFTKNPSTRL WPVLETDEVVRSLIDGILTN KKMIFVPSYINIFLRLQKF
Tissue Specificity Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
Function Plays a pivotal role in hepatic lipid metabolism. In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4. Isoform 2: Has retinol/retinal dehydrogenase activity in vitro. Isoform 1: Does not have retinol/retinal dehydrogenase activity in vitro.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase 13
17-Beta-Hsd 13
Hepatic Retinol/Retinal Dehydrogenase
Short Chain Dehydrogenase/Reductase Family 16c Member 3
Short-Chain Dehydrogenase/Reductase 9
Database Links Reactome: R-HSA-8964572
Cellular Localisation Isoform 2: Lipid Droplet
Endoplasmic Reticulum
Redistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet Formation
Isoform 1: Cytoplasm
Does Not Localize To Lipid Droplets
Alternative Antibody Names Anti-17-Beta-Hydroxysteroid Dehydrogenase 13 antibody
Anti-17-Beta-Hsd 13 antibody
Anti-Hepatic Retinol/Retinal Dehydrogenase antibody
Anti-Short Chain Dehydrogenase/Reductase Family 16c Member 3 antibody
Anti-Short-Chain Dehydrogenase/Reductase 9 antibody
Anti-HSD17B13 antibody
Anti-SCDR9 antibody
Anti-SDR16C3 antibody
Anti-HMFN0376 antibody
Anti-UNQ497 antibody
Anti-PRO1014 antibody

Information sourced from Uniprot.org

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