| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine protease hepsin (350-430 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HPN |
| Gene ID: | 3249 |
| Uniprot ID: | HEPS_HUMAN |
| Immunogen Region: | 350-430 aa |
| Specificity: | HEPS Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 350-430 |
| Function | Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. |
| Protein Name | Serine Protease HepsinTransmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Serine Protease Hepsin antibodyAnti-Transmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain antibodyAnti-HPN antibodyAnti-TMPRSS1 antibody |
Information sourced from Uniprot.org