| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HPD |
| Gene ID: | 3242 |
| Uniprot ID: | HPPD_HUMAN |
| Immunogen Region: | 1-393 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human HPD (NP_002141.1). |
| Immunogen Sequence: | MTTYSDKGAKPERGRFLHFH SVTFWVGNAKQAASFYCSKM GFEPLAYRGLETGSREVVSH VIKQGKIVFVLSSALNPWNK EMGDHLVKHGDGVKDIAFEV EDCDYIVQKARERGAKIMRE PWVEQDKFGKVKFAVLQTYG DTTHTLVEKMNYIGQFLPGY EAPAFMDPLLPKLPKCSLEM IDHIVGNQPDQEMVSASEWY LKNLQFHRFWSVDDTQVHTE YSSLRSIVVANYEESIKMP |
| Function | Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism. |
| Protein Name | 4-Hydroxyphenylpyruvate Dioxygenase4-Hydroxyphenylpyruvic Acid Oxidase4hppdHpdHppdase |
| Database Links | Reactome: R-HSA-8963684 |
| Cellular Localisation | CytoplasmEndoplasmic Reticulum MembranePeripheral Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-4-Hydroxyphenylpyruvate Dioxygenase antibodyAnti-4-Hydroxyphenylpyruvic Acid Oxidase antibodyAnti-4hppd antibodyAnti-Hpd antibodyAnti-Hppdase antibodyAnti-HPD antibodyAnti-PPD antibody |
Information sourced from Uniprot.org