• Immunohistochemical analysis of paraffin-embedded Human-lung-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded Human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded Human-lung-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded Human-liver, antibody was diluted at 1:100

Anti-HP antibody (300-360 aa) (STJ98976)

SKU:
STJ98976

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Haptoglobin (300-360 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HP
Gene ID: 3240
Uniprot ID: HPT_HUMAN
Immunogen Region: 300-360 aa
Specificity: The antibody detects endogenous Haptoglobin
Immunogen: Synthetic peptide from the human protein at the amino acid range 300-360
Function As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. The uncleaved form of allele alpha-2 (2-2), known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Protein Name Haptoglobin
Zonulin Cleaved Into - Haptoglobin Alpha Chain - Haptoglobin Beta Chain
Database Links Reactome: R-HSA-2168880
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Haptoglobin antibody
Anti-Zonulin Cleaved Into - Haptoglobin Alpha Chain - Haptoglobin Beta Chain antibody
Anti-HP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance