Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Heterogeneous nuclear ribonucleoprotein D-like (241-290 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HNRNPDL |
Gene ID: |
9987 |
Uniprot ID: |
HNRDL_HUMAN |
Immunogen Region: |
241-290 aa |
Specificity: |
hnRNP DL Polyclonal Antibody detects endogenous levels of hnRNP DL protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human HNRPDL at the amino acid range 241-290 |
Post Translational Modifications | Dimethylation of Arg-408 is probably of the asymmetric type. |
Function | Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. |
Protein Name | Heterogeneous Nuclear Ribonucleoprotein D-LikeHnrnp D-LikeHnrnp DlAu-Rich Element Rna-Binding FactorJkt41-Binding ProteinProtein Laauf1 |
Database Links | Reactome: R-HSA-8950505 |
Cellular Localisation | NucleusCytoplasmShuttles Between The Nucleus And The Cytoplasm In A Tnpo1-Dependent Manner |
Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein D-Like antibodyAnti-Hnrnp D-Like antibodyAnti-Hnrnp Dl antibodyAnti-Au-Rich Element Rna-Binding Factor antibodyAnti-Jkt41-Binding Protein antibodyAnti-Protein Laauf1 antibodyAnti-HNRNPDL antibodyAnti-HNRPDL antibodyAnti-JKTBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance