Post Translational Modifications | Dimethylation of Arg-408 is probably of the asymmetric type. |
Function | Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. |
Protein Name | Heterogeneous Nuclear Ribonucleoprotein D-LikeHnrnp D-LikeHnrnp DlAu-Rich Element Rna-Binding FactorJkt41-Binding ProteinProtein Laauf1 |
Database Links | Reactome: R-HSA-8950505 |
Cellular Localisation | NucleusCytoplasmShuttles Between The Nucleus And The Cytoplasm In A Tnpo1-Dependent Manner |
Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein D-Like antibodyAnti-Hnrnp D-Like antibodyAnti-Hnrnp Dl antibodyAnti-Au-Rich Element Rna-Binding Factor antibodyAnti-Jkt41-Binding Protein antibodyAnti-Protein Laauf1 antibodyAnti-HNRNPDL antibodyAnti-HNRPDL antibodyAnti-JKTBP antibody |
Information sourced from Uniprot.org