• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HNRPDL Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-HNRNPDL antibody (241-290 aa) (STJ93563)

SKU:
STJ93563

Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Heterogeneous nuclear ribonucleoprotein D-like (241-290 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HNRNPDL
Gene ID: 9987
Uniprot ID: HNRDL_HUMAN
Immunogen Region: 241-290 aa
Specificity: hnRNP DL Polyclonal Antibody detects endogenous levels of hnRNP DL protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HNRPDL at the amino acid range 241-290
Post Translational Modifications Dimethylation of Arg-408 is probably of the asymmetric type.
Function Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.
Protein Name Heterogeneous Nuclear Ribonucleoprotein D-Like
Hnrnp D-Like
Hnrnp Dl
Au-Rich Element Rna-Binding Factor
Jkt41-Binding Protein
Protein Laauf1
Database Links Reactome: R-HSA-8950505
Cellular Localisation Nucleus
Cytoplasm
Shuttles Between The Nucleus And The Cytoplasm In A Tnpo1-Dependent Manner
Alternative Antibody Names Anti-Heterogeneous Nuclear Ribonucleoprotein D-Like antibody
Anti-Hnrnp D-Like antibody
Anti-Hnrnp Dl antibody
Anti-Au-Rich Element Rna-Binding Factor antibody
Anti-Jkt41-Binding Protein antibody
Anti-Protein Laauf1 antibody
Anti-HNRNPDL antibody
Anti-HNRPDL antibody
Anti-JKTBP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance