| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hepatocyte nuclear factor 4-alpha (280-329 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HNF4A |
| Gene ID: |
3172 |
| Uniprot ID: |
HNF4A_HUMAN |
| Immunogen Region: |
280-329 aa |
| Specificity: |
HNF-4 Alpha Polyclonal Antibody detects endogenous levels of HNF-4 Alpha protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human HNF4 alpha at the amino acid range 280-329 |
| Function | Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. Activates the transcription of CYP2C38. Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells. |
| Protein Name | Hepatocyte Nuclear Factor 4-AlphaHnf-4-AlphaNuclear Receptor Subfamily 2 Group A Member 1Transcription Factor 14Tcf-14Transcription Factor Hnf-4 |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hepatocyte Nuclear Factor 4-Alpha antibodyAnti-Hnf-4-Alpha antibodyAnti-Nuclear Receptor Subfamily 2 Group A Member 1 antibodyAnti-Transcription Factor 14 antibodyAnti-Tcf-14 antibodyAnti-Transcription Factor Hnf-4 antibodyAnti-HNF4A antibodyAnti-HNF4 antibodyAnti-NR2A1 antibodyAnti-TCF14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
