| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Biotin--protein ligase ligase; Biotin--propionyl-CoA-carboxylase ligase; Biotin--methylcrotonoyl-CoA-carboxylase ligase; Biotin--acetyl-CoA-carboxylase ligase is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HLCS |
| Gene ID: | 3141 |
| Uniprot ID: | BPL1_HUMAN |
| Specificity: | This antibody detects endogenous levels of HLCS at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human HLCS |
| Function | Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase. |
| Protein Name | Biotin--Protein LigaseBiotin Apo-Protein Ligase Includes - Biotin--Methylmalonyl-Coa-Carboxytransferase Ligase - Biotin--Propionyl-Coa-Carboxylase Atp-Hydrolyzing LigaseHolocarboxylase SynthetaseHcs - Biotin--Methylcrotonoyl-Coa-Carboxylase Ligase - Biotin--Acetyl-Coa-Carboxylase Ligase |
| Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Biotin--Protein Ligase antibodyAnti-Biotin Apo-Protein Ligase Includes - Biotin--Methylmalonyl-Coa-Carboxytransferase Ligase - Biotin--Propionyl-Coa-Carboxylase Atp-Hydrolyzing Ligase antibodyAnti-Holocarboxylase Synthetase antibodyAnti-Hcs - Biotin--Methylcrotonoyl-Coa-Carboxylase Ligase - Biotin--Acetyl-Coa-Carboxylase Ligase antibodyAnti-HLCS antibody |
Information sourced from Uniprot.org