Anti-HINFP antibody (258-517 aa) (STJ11107430)

SKU:
STJ11107430
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: HINFP
Gene ID: 25988
Uniprot ID: HINFP_HUMAN
Immunogen Region: 258-517 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 258-517 of human HINFP (NP_945322.1).
Immunogen Sequence: PLCDMTCPLPSSLRNHMRFR HSEDRPFKCDCCDYSCKNLI DLQKHLDTHSEEPAYRCDFE NCTFSARSLCSIKSHYRKVH EGDSEPRYKCHVCDKCFTRG NNLTVHLRKKHQFKWPSGHP RFRYKEHEDGYMRLQLVRYE SVELTQQLLRQPQEGSGLGT SLNESSLQGIILETVPGEPG RKEEEEEGKGSEGTALSASQ DNPSSVIHVVNQTNAQGQQE IVYYVLSEAPGEPPPAPEP
Tissue Specificity Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver.
Post Translational Modifications Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation.
Function Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
Protein Name Histone H4 Transcription Factor
Histone Nuclear Factor P
Hinf-P
Mbd2-Interacting Zinc Finger Protein
Methyl-Cpg-Binding Protein 2-Interacting Zinc Finger Protein
Cellular Localisation Nucleus
Associated With Discrete Nuclear Foci
Alternative Antibody Names Anti-Histone H4 Transcription Factor antibody
Anti-Histone Nuclear Factor P antibody
Anti-Hinf-P antibody
Anti-Mbd2-Interacting Zinc Finger Protein antibody
Anti-Methyl-Cpg-Binding Protein 2-Interacting Zinc Finger Protein antibody
Anti-HINFP antibody
Anti-MIZF antibody
Anti-ZNF743 antibody

Information sourced from Uniprot.org

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