| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
HINFP |
| Gene ID: |
25988 |
| Uniprot ID: |
HINFP_HUMAN |
| Immunogen Region: |
258-517 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 258-517 of human HINFP (NP_945322.1). |
| Immunogen Sequence: |
PLCDMTCPLPSSLRNHMRFR HSEDRPFKCDCCDYSCKNLI DLQKHLDTHSEEPAYRCDFE NCTFSARSLCSIKSHYRKVH EGDSEPRYKCHVCDKCFTRG NNLTVHLRKKHQFKWPSGHP RFRYKEHEDGYMRLQLVRYE SVELTQQLLRQPQEGSGLGT SLNESSLQGIILETVPGEPG RKEEEEEGKGSEGTALSASQ DNPSSVIHVVNQTNAQGQQE IVYYVLSEAPGEPPPAPEP |
| Tissue Specificity | Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver. |
| Post Translational Modifications | Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation. |
| Function | Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. |
| Protein Name | Histone H4 Transcription FactorHistone Nuclear Factor PHinf-PMbd2-Interacting Zinc Finger ProteinMethyl-Cpg-Binding Protein 2-Interacting Zinc Finger Protein |
| Cellular Localisation | NucleusAssociated With Discrete Nuclear Foci |
| Alternative Antibody Names | Anti-Histone H4 Transcription Factor antibodyAnti-Histone Nuclear Factor P antibodyAnti-Hinf-P antibodyAnti-Mbd2-Interacting Zinc Finger Protein antibodyAnti-Methyl-Cpg-Binding Protein 2-Interacting Zinc Finger Protein antibodyAnti-HINFP antibodyAnti-MIZF antibodyAnti-ZNF743 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
