| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-HFE (249-348) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HFE |
| Gene ID: |
3077 |
| Uniprot ID: |
HFE_HUMAN |
| Immunogen Region: |
249-348 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201). |
| Immunogen Sequence: |
KEFEPKDVLPNGDGTYQGWI TLAVPPGEEQRYTCQVEHPG LDQPLIVIWEPSPSGTLVIG VISGIAVFVVILFIGILFII LRKRQGSRGAMGHYVLAERE |
| Tissue Specificity | Expressed in all tissues tested except brain. |
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hereditary Hemochromatosis Protein antibodyAnti-Hla-H antibodyAnti-HFE antibodyAnti-HLAH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
