| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
HECTD3 |
| Gene ID: |
79654 |
| Uniprot ID: |
HECD3_HUMAN |
| Immunogen Region: |
642-861 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 642-861 of human HECTD3 (NP_078878.3). |
| Immunogen Sequence: |
DSVLVKLLEVMEGMDKETFE FKFGKELTFTTVLSDQQVVE LIPGGAGIVVGYGDRSRFIQ LVQKARLEESKEQVAAMQAG LLKVVPQAVLDLLTWQELEK KVCGDPEVTVDALRKLTRFE DFEPSDSRVQYFWEALNNFT NEDRSRFLRFVTGRSRLPAR IYIYPDKLGYETTDALPESS TCSSTLFLPHYASAKVCEEK LRYAAYNCVAIDTDMSPWEE |
| Function | E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8. |
| Protein Name | E3 Ubiquitin-Protein Ligase Hectd3Hect Domain-Containing Protein 3Hect-Type E3 Ubiquitin Transferase Hectd3 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Hectd3 antibodyAnti-Hect Domain-Containing Protein 3 antibodyAnti-Hect-Type E3 Ubiquitin Transferase Hectd3 antibodyAnti-HECTD3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
